Behavioural crisis / agitation
A streamlined, differential-led presentation for rapid clinical review.
Twenty-second review
- Agitation may arise from psychiatric illness, intoxication, withdrawal, delirium, hypoxia, head injury, glucose disturbance, or hyperthermic toxic physiology.
- Immediate violence risk, extreme exertion, hyperthermia, altered LOC, focal deficit, severe intoxication, or respiratory compromise requires urgent coordinated care.
- Keep hypoglycemia or hypoxia in the differential; overlapping or concurrent illness remains possible.
- For behavioural crisis / agitation, trends and combinations of findings are more informative than one isolated vital sign.
Compare the clinical patterns
The repeated material is grouped inside each possibility. Open only the condition you need.
DeliriumTime-sensitive high-risk possibility
HPI
Clarify immediate safety risks; baseline and precipitating event; medical causes and trauma.
Signs & symptoms
Fluctuation, abnormal vitals, focal signs, trauma, or hyperthermia.
Focused exam
Observe behaviour, speech, thought process, perception, orientation, attention, and signs of intoxication, injury, or medical illness; Assess risk using direct questions and collateral information.
Brief pathophysiology
Delirium may cause behavioural crisis / agitation through a time-sensitive process capable of rapid physiological deterioration.
What the trend may show
There is no diagnostic vital-sign pattern for a behavioural, functional, or social presentation. Abnormal physiology should be explained and may indicate delirium, toxicity, infection, trauma, or another medical cause.
Temperature (°C)
Screen for medical causeFever or hypothermia suggests infection, exposure, or toxicity.
Blood glucose (mmol/L)
Check when indicatedGlucose disturbance can cause altered behaviour or weakness.
Heart rate (bpm)
Explain abnormalitiesTachycardia may reflect distress but should not be dismissed.
Blood pressure (mmHg)
Compare with baselineHypotension or severe hypertension warrants medical evaluation.
Front-load in the triage report
- Delirium: Fluctuation, abnormal vitals, focal signs, trauma, or hyperthermia.
- Immediate safety risks?
- Baseline and precipitating event?
Toxic syndromeTime-sensitive high-risk possibility
HPI
Clarify baseline and precipitating event; medical causes and trauma; substances or medication change.
Signs & symptoms
Fluctuation, abnormal vitals, focal signs, trauma, or hyperthermia.
Focused exam
Assess risk using direct questions and collateral information; Observe from a safe distance; assess attention, speech, thought, pupils, skin, temperature, glucose, trauma, substances, and restraint effects.
Brief pathophysiology
Toxic syndrome may cause behavioural crisis / agitation through a time-sensitive process capable of rapid physiological deterioration.
What the trend may show
There is no diagnostic vital-sign pattern for a behavioural, functional, or social presentation. Abnormal physiology should be explained and may indicate delirium, toxicity, infection, trauma, or another medical cause.
Temperature (°C)
Screen for medical causeFever or hypothermia suggests infection, exposure, or toxicity.
Blood glucose (mmol/L)
Check when indicatedGlucose disturbance can cause altered behaviour or weakness.
Heart rate (bpm)
Explain abnormalitiesTachycardia may reflect distress but should not be dismissed.
Blood pressure (mmHg)
Compare with baselineHypotension or severe hypertension warrants medical evaluation.
Front-load in the triage report
- Toxic syndrome: Fluctuation, abnormal vitals, focal signs, trauma, or hyperthermia.
- Baseline and precipitating event?
- Medical causes and trauma?
Intracranial diseaseTime-sensitive high-risk possibility
HPI
Clarify medical causes and trauma; substances or medication change; suicidal or homicidal thoughts.
Signs & symptoms
Fluctuation, abnormal vitals, focal signs, trauma, or hyperthermia.
Focused exam
Assess risk using direct questions and collateral information; Observe from a safe distance; assess attention, speech, thought, pupils, skin, temperature, glucose, trauma, substances, and restraint effects.
Brief pathophysiology
Intracranial disease may cause behavioural crisis / agitation through a time-sensitive process capable of rapid physiological deterioration.
What the trend may show
There is no diagnostic vital-sign pattern for a behavioural, functional, or social presentation. Abnormal physiology should be explained and may indicate delirium, toxicity, infection, trauma, or another medical cause.
Temperature (°C)
Screen for medical causeFever or hypothermia suggests infection, exposure, or toxicity.
Blood glucose (mmol/L)
Check when indicatedGlucose disturbance can cause altered behaviour or weakness.
Heart rate (bpm)
Explain abnormalitiesTachycardia may reflect distress but should not be dismissed.
Blood pressure (mmHg)
Compare with baselineHypotension or severe hypertension warrants medical evaluation.
Front-load in the triage report
- Intracranial disease: Fluctuation, abnormal vitals, focal signs, trauma, or hyperthermia.
- Medical causes and trauma?
- Substances or medication change?
PsychiatricCommon presentation pattern
HPI
Clarify immediate safety risks; baseline and precipitating event; medical causes and trauma.
Signs & symptoms
Behaviour may follow psychosis, mania, fear, or conflict.
Focused exam
Observe behaviour, speech, thought process, perception, orientation, attention, and signs of intoxication, injury, or medical illness; Assess risk using direct questions and collateral information.
Brief pathophysiology
Psychiatric may explain the presenting symptoms through a common clinical mechanism, while serial assessment checks for complications or an alternate cause.
What the trend may show
There is no diagnostic vital-sign pattern for a behavioural, functional, or social presentation. Abnormal physiology should be explained and may indicate delirium, toxicity, infection, trauma, or another medical cause.
Temperature (°C)
Screen for medical causeFever or hypothermia suggests infection, exposure, or toxicity.
Blood glucose (mmol/L)
Check when indicatedGlucose disturbance can cause altered behaviour or weakness.
Heart rate (bpm)
Explain abnormalitiesTachycardia may reflect distress but should not be dismissed.
Blood pressure (mmHg)
Compare with baselineHypotension or severe hypertension warrants medical evaluation.
Front-load in the triage report
- Behaviour may follow psychosis, mania, fear, or conflict.
- Immediate safety risks?
- Baseline and precipitating event?
Situational agitationCommon presentation pattern
HPI
Clarify baseline and precipitating event; medical causes and trauma; substances or medication change.
Signs & symptoms
Behaviour may follow psychosis, mania, fear, or conflict.
Focused exam
Assess risk using direct questions and collateral information; Observe from a safe distance; assess attention, speech, thought, pupils, skin, temperature, glucose, trauma, substances, and restraint effects.
Brief pathophysiology
Situational agitation may explain the presenting symptoms through a common clinical mechanism, while serial assessment checks for complications or an alternate cause.
What the trend may show
There is no diagnostic vital-sign pattern for a behavioural, functional, or social presentation. Abnormal physiology should be explained and may indicate delirium, toxicity, infection, trauma, or another medical cause.
Temperature (°C)
Screen for medical causeFever or hypothermia suggests infection, exposure, or toxicity.
Blood glucose (mmol/L)
Check when indicatedGlucose disturbance can cause altered behaviour or weakness.
Heart rate (bpm)
Explain abnormalitiesTachycardia may reflect distress but should not be dismissed.
Blood pressure (mmHg)
Compare with baselineHypotension or severe hypertension warrants medical evaluation.
Front-load in the triage report
- Behaviour may follow psychosis, mania, fear, or conflict.
- Baseline and precipitating event?
- Medical causes and trauma?
HypoglycemiaImportant alternative presentation
HPI
Clarify immediate safety risks; baseline and precipitating event; medical causes and trauma.
Signs & symptoms
Reversible physiological causes can present primarily as agitation.
Focused exam
Observe behaviour, speech, thought process, perception, orientation, attention, and signs of intoxication, injury, or medical illness; Assess risk using direct questions and collateral information.
Brief pathophysiology
Hypoglycemia can resemble behavioural crisis / agitation through overlapping symptoms or referred physiology despite a different primary mechanism.
What the trend may show
Confirm low capillary glucose and reassess after treatment. Adrenergic signs may be absent in recurrent hypoglycemia or blunted by medications.
Blood glucose (mmol/L)
< 4.0 mmol/LBCEHS defines hypoglycemia as blood glucose below 4.0 mmol/L.
Heart rate (bpm)
May riseAdrenergic activation commonly produces tachycardia, but this is not universal.
Blood pressure (mmHg)
Often preservedBlood pressure is not a reliable discriminator; hypotension suggests another or additional process.
Temperature (°C)
May fallHypothermia can accompany prolonged or severe hypoglycemia.
Front-load in the triage report
- Reversible physiological causes can present primarily as agitation.
- Immediate safety risks?
- Baseline and precipitating event?
HypoxiaImportant alternative presentation
HPI
Clarify baseline and precipitating event; medical causes and trauma; substances or medication change.
Signs & symptoms
Reversible physiological causes can present primarily as agitation.
Focused exam
Assess risk using direct questions and collateral information; Observe from a safe distance; assess attention, speech, thought, pupils, skin, temperature, glucose, trauma, substances, and restraint effects.
Brief pathophysiology
Hypoxia can resemble behavioural crisis / agitation through overlapping symptoms or referred physiology despite a different primary mechanism.
What the trend may show
There is no diagnostic vital-sign pattern for a behavioural, functional, or social presentation. Abnormal physiology should be explained and may indicate delirium, toxicity, infection, trauma, or another medical cause.
Temperature (°C)
Screen for medical causeFever or hypothermia suggests infection, exposure, or toxicity.
Blood glucose (mmol/L)
Check when indicatedGlucose disturbance can cause altered behaviour or weakness.
Heart rate (bpm)
Explain abnormalitiesTachycardia may reflect distress but should not be dismissed.
Blood pressure (mmHg)
Compare with baselineHypotension or severe hypertension warrants medical evaluation.
Front-load in the triage report
- Reversible physiological causes can present primarily as agitation.
- Baseline and precipitating event?
- Medical causes and trauma?
Findings that should escalate concern
- Excited delirium features
- Hyperthermia
- Severe exhaustion
- Threat to self or others
- Immediate violence risk, extreme exertion, hyperthermia, altered LOC, focal deficit, severe intoxication, or respiratory compromise requires urgent coordinated care.
- Delirium, toxic syndrome, or intracranial disease: Fluctuation, abnormal vitals, focal signs, trauma, or hyperthermia.
Medication recognition
Continue the clinical pathway
Clinical and academic sources
Curated clinical guidance and peer-reviewed evidence supporting this presentation. Current BCEHS guidance, medical direction, and local policy remain authoritative for practice.
BCEHS Handbook — specific CPGs
Supporting clinical and academic evidence
- CEDIS Presenting Complaint List updateCanadian Association of Emergency Physicians
Presenting-complaint terminology and categorization context. It does not establish a prehospital “top 100” ranking.
- Self-harm: assessment, management and preventing recurrenceNational Institute for Health and Care Excellence
Evidence-based psychosocial assessment, safety, communication, and risk-management guidance.
- Management of the Agitated PatientEmergency Medicine Clinics of North America · 2024
Medical causes, verbal de-escalation, safety, monitoring, and proportionate management of acute agitation.