Cardiovascular
Sacubitril/valsartan
Entresto
Generic nameSacubitril/valsartan
Brand nameEntresto
Medication classARNI
Typical adult example24/26–97/103 mg
FrequencyTwice daily
Common uses
Recognition cues
- Heart failure with reduced ejection fraction
EMS relevance
Assessment context
- May cause hypotension or hyperkalemia; do not combine closely with an ACE inhibitor.